Tamiflu er et antiviralt middel, der anvendes til indlæggelseskrævende influenza. Se også Xofluza.
- Aktivt stof: Oseltamivir
- Produktnavne: Tamiflu
- ATC-kode: J05AH02
Indikation & dosisforslag
Ved Influenza:
- Tamiflu 75 mg x 2 i 5 dage
Studier
- To systematisk reviews viste at Tamiflu ikke forebyggede indlæggelser, men gav GI-bivirkninger [B1, B2], mens to andre reviews viste en effekt [B3, B4].
Referencer
A. Generelle referencer
B. Studier
- Hanula R, Bortolussi-Courval É, Mendel A, Ward BJ, Lee TC, McDonald EG. Evaluation of Oseltamivir Used to Prevent Hospitalization in Outpatients With Influenza: A Systematic Review and Meta-analysis. JAMA Intern Med. 2023 Jun 12:e230699. doi: 10.1001/jamainternmed.2023.0699. Epub ahead of print. PMID: 37306992; PMCID: PMC10262060.
- Jefferson T, Jones M, Doshi P, Spencer EA, Onakpoya I, Heneghan CJ. Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments. BMJ. 2014 Apr 9;348:g2545. doi: 10.1136/bmj.g2545. PMID: 24811411; PMCID: PMC3981975.
- Kaiser L, Wat C, Mills T, Mahoney P, Ward P, Hayden F. Impact of oseltamivir treatment on influenza-related lower respiratory tract complications and hospitalizations. Arch Intern Med. 2003 Jul 28;163(14):1667-72. doi: 10.1001/archinte.163.14.1667. PMID: 12885681.
- Dobson J, Whitley RJ, Pocock S, Monto AS. Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials. Lancet. 2015 May 2;385(9979):1729-1737. doi: 10.1016/S0140-6736(14)62449-1. Epub 2015 Jan 30. Erratum in: Lancet. 2015 May 2;385(9979):1728. Erratum in: Lancet. 2015 May 2;385(9979):1728. PMID: 25640810.
Sidst opdateret 27. juni 2023